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Fenugreek has been used for thousands of years both as medicine and spice in Egypt, India and the Middle East. Traditional uses of medicines include treatment of wounds, bronchitis, digestive problems, arthritis, kidney problems, male reproductive conditions, boils, diabetes, cellulitis, tuberculosis, and gastrointestinal problems. Animal research has found that the seeds to reduce serum cholesterol and glucose levels.

The active components fenugreek are mucilages, proteins, steroid saponins, flavonoids and volatile oils. Trigonelline, an alkaloid found in fenugreek, is degraded to nicotinic acid (niacin), which may partly explain the ability of serum cholesterol levels. Steroidal saponins blood glucose and may also decrease plasma glucagon and improve food intake and appetite. The seeds contain up to 50% fiber gel that due to its ability to absorb and expand, are commonly used to treat diarrhea and constipation. The seeds also contain coumarin compounds. Fenugreek is available in capsules, paste, powder, ripe seeds, dried seeds, and as spice.

Uses Reported

Fenugreek is used to treat gastrointestinal disorders and to relieve congestion and upper respiratory allergies. Also is used to lower cholesterol, blood glucose, insulin levels and hemoglobin ALS, improve glucose tolerance, and as an appetite stimulant.

A topical preparation of fenugreek is applied to treat skin inflammation, muscle pain, and gout, and assist the healing of wounds or ulcers in the skin.

Terminal

External: A poultice is prepared by mixing 50 g of powdered fenugreek with 1 quart (1 L) of water and applied topically in the affected area as needed

Internal: An infusion is prepared by the fermentation of 0.5 g of fenugreek in cold water for 3 hours, then stretched. Honey can be used to sweeten tea. The dose is 6 g by mouth or a cup of tea taken several times a day.

Hazards

Adverse effects include fenugreek odor of maple syrup urine, hepatotoxicity, jaundice, nausea, vomiting, increased bilirubin, hypoglycemia, dermatitis contact (external use), flushing, wheezing, watery eyes, numbness, rash, and angioedema (after inhalation, ingestion or topical anesthesia).

When taken with the blockers, there is an additive vasodilating effect may lead to hypotension. There is a risk most of the prothrombin time (PT) and International Normalized Ratio (INR), and the potential risk of abnormal bleeding when taken with anticoagulants fenugreek as aspirin, NSAIDs, heparin, low weight Molecular and warfarin. Fenugreek also has the potential to reduce the rate of blood glucose when administered to those taking antidiabetic agents, including insulin. Effect uricosuric probencid decrease is observed and sulfinpyrazone. Because the fiber content of fenugreek seeds and its possible link, drug absorption can be altered. Advise patients to avoid using fenugreek within 2 hours of other drugs.

Pregnant women should avoid use because of the abortifacient properties potential of the plant, and water-alcohol extract of the plant May stimulate uterine activity. People with liver disease, peptic ulcer, or hypotension severe should avoid due to the formation of nicotinic acid. Breast feeding patients, and those who had an allergic reaction to fenugreek reaction or nicotinic acid should be avoided.

Clinical Considerations

If the patient taking an anticoagulant, monitor PTT, INR, and PT. Monitor the patient for abnormal bleeding.

Appearance of rash or contact dermatitis may indicate sensitivity to fenugreek.

Nausea, vomiting, jaundice, or increase the level of bilirubin can indicate liver damage and hepatotoxicity of nicotinic acid. If the patient develops these signs or symptoms, immediately should stop using the herbs.

If the patient is pregnant, taking into account pregnancy or breastfeeding are advised not to use fenugreek.

Caution patients that rash or abnormal change may indicate an allergy to fenugreek and nausea, vomiting, and changes in skin color may indicate damage liver. Tell patients to stop using, whether the signs and symptoms appear.

Remind patients not to take Fenugreek at the same time as other drugs and to separate the administration time of 2 hours.

Tell patient to remind pharmacist of any nutritional supplement herbal or taken in obtaining a new prescription.

Advise patient to consult your health care before using a plant health preparedness, since treatment proven conventional may be available.

Search Summary

Current studies continue to elucidate the mechanism of the ability of fenugreek to lower cholesterol and blood sugar. Recent studies also show the capacity of the plant to reduce the amount of calcium oxalate deposited in the kidneys.

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